Zenbioisproudtoofferseveralnon-animalreplacementsforFetalBovineSerum(FBS):HumanPlateletLysate-(New!),GroProready-to-usegrowthsupplementandHumanABSerum.

ZenBio,Inc.IntroducesGroPro™CellCultureGrowthSupplement
FormulatedtoReplaceBovineSerumAllowingforCulturingof
PrimaryCellsandCellLines

OurNEW!HumanPlateletLysate(HPL)andGroProareanon-animalderivedcellculturegrowthsupplementsobtainedfromhumanplatelets.HPLcontainsabundantgrowthfactorsandcytokinesnecessaryforcellgrowthandproliferation.PlateletlysatecanbeusedasareplacementfortrADItionalFetalBovine(FBS)supplementedcellculturemedium.Replacingfetalbovineserum(FBS)withHPLallowsforexpansionandpotentialclinicalgradeproductionoffunctionalmesenchymalstromalcellsbyremovingtheriskofxenogeneicimmunereactionsandtransmissionofbovineprionandviralpathogens.Additionally,HPLandGroProarederivedfromarenewablesourcethatisnottiedtotheanimalslaughterindustryandthepricedoesnotfluctuate!

TheUSFDAismovingtowardsadoptingEuropeanguidelinesrequiringthatbovinematerialsberemovedfromculturingmediaforanytherapeuticproductcontainingculturedcells,thusmakingHPLanattractivealternativetotheR&Dandproduction/manufacturingprocesses.AlllotsarefullytestedforpathogensaccordingtoFDAguidelines.

• 10XmorepotentthanFBS
• StablePricing
• Non-AnimalDerived
• TraceABIlity
• FreeofMycoplasma
• Lot-to-LotConsistency
• SterileCollection
• PoolProcessing
• QCTestedinZenBio"sCellProductionSystem

HumanABSerum:

Humanserumoffersatechnicaladvantageoveranimalserumwhenculturingavarietyofhumancelltypes,especiallythosecellsmakinguptheimmunesystem.Thisisalsotheserumofchoicewhendevelopingtissueengineeredandregenerativemedicineproducts,asmanyregulatoryagenciesinagrowingnumberofcountriesarerestrictingtheuseofanimalserumduringthemanufacturingprocess.

SincehumanserumfromtypeABdonorsislackinginantibodiestowardstheAandBblood-typeantigens,thisisthetypemostcommonlyusedasimmunoreactivityisminimizedagainstthehumancellsinculture.Maledonorserumispreferredoverfemale,asthislowerstheriskofmajorhistocompatibilityclass(MHC)antibodiesbeingpresent.WomenhavingapastpregnancymayhavedevelopedtheseantibodiestoMHCantigenscarriedonthefather"scellsorthedevelopingfetus.

Zenbio成立于1995年，自其成立起就在持续供货和扩大研发方面一直处于领先地位，Zenbio以其国际水平的技术支持和专注的客户服务，得到了广泛的认可。Zenbio的成立致力于满足研究人员对肥胖者、糖尿病和心血管疾病研究的迫切需要。尽管啮齿类动物模型对研究新陈代谢各种通路极为有用，但人体的病理学研究关键分析仍需要适合的体外模型，用以研究人的脂肪细胞。而Zenbio能够为研究者提供多种细胞作为病理学研究模型。产品主要包括人类原代细胞、细胞系、培养基、及代谢疾病和药用化妆品等方面的检测试剂盒。